2025 Publications

McNitt SA, Dick JK, Hernandez-Castaneda MA, Sangala J, Pierson M, Macchietto M, Burrack KS, Crompton PD, Seydel K, Hamilton SE, Hart GT.
JCI Insight. 2025 May 8;10(9):e183076. doi: 10.1172/jci.insight.183076. eCollection 2025 May 8.
PMID: 40337867

Metagenomic source tracking after microbiota transplant therapy.
Hoops SL, Moutsoglou D, Vaughn BP, Khoruts A, Knights D.
Gut Microbes. 2025 Dec;17(1):2487840. doi: 10.1080/19490976.2025.2487840. Epub 2025 Apr 14.
PMID: 40229213

Rabies vaccination induces a CD4+ TEM and CD4+CD8+ TEMRA TH1 phenotype in dogs.
Lang HP, Almeer FF, Jenkins MK, Friedenberg SG.
PLoS One. 2025 May 12;20(5):e0323823. doi: 10.1371/journal.pone.0323823. eCollection 2025.
PMID: 40354406

Divergent immediate and delayed effects of juvenile exposure to doxorubicin on the thymus in C57BL/6 mice.
George B, Dahlquist KJV, Grant MKO, Daniel MR, Smith DM, Ahlberg I, Sadak KT, Seelig D, Camell CD, Zordoky BN.
Sci Rep. 2025 May 3;15(1):15557. doi: 10.1038/s41598-025-98617-5.
PMID: 40319158

Wang H, Herman A, Barrow F, Abdel-Ghani A, Draxler M, Fredrickson G, Parthiban P, Seelig DM, Ikramuddin S, Revelo XS.
Hepatol Commun. 2025 Apr 21;9(5):e0668. doi: 10.1097/HC9.0000000000000668. eCollection 2025 May 1.
PMID: 40257356

Rehermann B, Graham AL, Masopust D, Hamilton SE.
Nat Rev Immunol. 2025 May;25(5):385-397. doi: 10.1038/s41577-024-01108-3. Epub 2024 Nov 19.
PMID: 39562646

Walton AH, Mazer MB, Remy KE, Osborne DF, Davitt EB, Griffith TS, Gould RW, Badovinac VP, Brakenridge SC, Drewry AM, Ungaro RF, Rocha IL, Loftus TJ, Efron PA, Moldawer LL, Caldwell CC, Hotchkiss RS.
Sci Rep. 2025 Apr 18;15(1):13464. doi: 10.1038/s41598-025-92016-6.
PMID: 40251188

Martinez RJ, Hogquist KA.
J Immunol. 2025 Apr 4:vkaf048. doi: 10.1093/jimmun/vkaf048. Online ahead of print.
PMID: 40184034

Severe malaria enforces short-lived effector cell differentiation but does not prevent effective secondary responses by memory CD8 T cells.
Hildebrand JA, Daniels NR, Dehm EM, Fisher BD, Guter JK, Janse CJ, Lucas ED, Sangala JA, Tankersley TN, Hart GT, Hamilton SE.
PLoS Pathog. 2025 Mar 31;21(3):e1012993. doi: 10.1371/journal.ppat.1012993. eCollection 2025 Mar.
PMID: 40163479

Polymorphisms in Pfkelch13 domains before and after the introduction of artemisinin-based combination therapy in Southwest Nigeria.
Amusan A, Akinola O, Akano K, Hernández-Castañeda M, Dick JK, Sowunmi A, Hart G, Gbotosho G.
PLoS One. 2025 Mar 31;20(3):e0316479. doi: 10.1371/journal.pone.0316479. eCollection 2025.
PMID: 40163420

Best practices in islet transplantation in mice.
Meier RPH, Ben Nasr M, Fife BT, Finger EB, Fiorina P, Luo X, Bromberg JS.
Am J Transplant. 2025 Mar 13:S1600-6135(25)00137-6. doi: 10.1016/j.ajt.2025.03.008. Online ahead of print.
PMID: 40089068

Collaboration between interleukin-7 and -15 enables adaptation of tissue-resident and circulating memory CD8⁺ T cells to cytokine deficiency.

Jarjour NN, Dalzell TS, Maurice NJ, Wanhainen KM, Peng C, O'Flanagan SD, DePauw TA, Block KE, Valente WJ, Ashby KM, Masopust D, Jameson SC.
Immunity. 2025 Mar 11;58(3):616-631.e5. doi: 10.1016/j.immuni.2025.02.009. Epub 2025 Feb 28.
PMID: 40023156

Risk Factors for Antibiotic Exposure Post-Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection: A Prospective Multicenter Observational Study.
Hirsch W, Fischer M, Khoruts A, Allegretti JR, Kelly CR, Vaughn B.
Open Forum Infect Dis. 2025 Mar 7;12(3):ofaf130. doi: 10.1093/ofid/ofaf130. eCollection 2025 Mar.
PMID: 40103733

Husmann R, Lehman A, Nelson RW, Pragman AA.
Clin Chest Med. 2025 Mar;46(1):61-75. doi: 10.1016/j.ccm.2024.10.005. Epub 2024 Nov 29.
PMID: 39890293

Saavedra FM, Brotto DB, Joag V, Matson CA, Herzberg MC, Nesmiyanov PP, Vezys V, Masopust D, Stolley JM.
Mucosal Immunol. 2025 Feb 21:S1933-0219(25)00021-2. doi: 10.1016/j.mucimm.2025.02.003. Online ahead of print.
PMID: 39988203

B-cell interleukin 1 receptor 1 modulates the female adipose tissue immune microenvironment during aging.

Carey A, Pitcher LE, Jang IH, Nguyen K, Cholensky S, Robbins PD, Camell CD.
J Leukoc Biol. 2025 Feb 13;117(2):qiae219. doi: 10.1093/jleuko/qiae219.
PMID: 39378334

Review of Elevated Para-Cresol in Autism and Possible Impact on Symptoms.

Flynn CK, Adams JB, Krajmalnik-Brown R, Khoruts A, Sadowsky MJ, Nirmalkar K, Takyi E, Whiteley P.
Int J Mol Sci. 2025 Feb 11;26(4):1513. doi: 10.3390/ijms26041513.
PMID: 40003979

Comparison of naturalization mouse model setups uncover distinct effects on intestinal mucosa depending on microbial experience.

Arnesen H, Birkeland S, Stendahl H, Neuhaus K, Masopust D, Boysen P, Carlsen H.
Discov Immunol. 2025 Feb 1;4(1):kyaf002. doi: 10.1093/discim/kyaf002. eCollection 2025.
PMID: 40065807

Viral Burden and Illness Severity During Acute SARS-CoV-2 Infection Predict Persistent Long COVID Symptoms.

Brandstetter Figueroa E, Frosch AEP, Burrack KS, Dileepan G, Goldsmith R, Harris M, Ikeogu N, Jibrell H, Thayalan S, Dewar RL, Shenoy C, Sereti I, Baker JV.
Open Forum Infect Dis. 2025 Jan 30;12(2):ofaf048. doi: 10.1093/ofid/ofaf048. eCollection 2025 Feb.
PMID: 39917335

A minority of Th1 and Tfh effector cells express survival genes shared by memory cell progeny that require IL-7 or TCR signaling to persist.

Osum KC, Becker SH, Krueger PD, Mitchell JS, Hong SW, Magill IR, Jenkins MK.
Cell Rep. 2025 Jan 28;44(1):115111. doi: 10.1016/j.celrep.2024.115111. Epub 2024 Dec 25.
PMID: 39723889

Reddi S, Senyshyn L, Ebadi M, Podlesny D, Minot SS, Gooley T, Kabage AJ, Hill GR, Lee SJ, Khoruts A, Rashidi A.
Nat Commun. 2025 Jan 25;16(1):1034. doi: 10.1038/s41467-025-56375-y.
PMID: 39863610

CD44 in myEloid cells is a major driver of liver inflammation and injury in alcohol-related liver disease.
Rousseau D, Bonnafous S, Soysouvanh F, Sarrail D, Bourinet M, Strazzulla A, Patouraux S, Borderie A, Dolfi B, Gallerand A, Farrugia MA, Orian-Rousseau V, Xu Y, Williams JW, Ivanov S, Tran A, Anty R, Luci C, Gual P.
Hepatology. 2025 Jan 14. doi: 10.1097/HEP.0000000000001232. Online ahead of print.
PMID: 39808819

Deep profiling deconstructs features associated with memory CD8⁺ T cell tissue residence.
Scott MC, Steier Z, Pierson MJ, Stolley JM, O'Flanagan SD, Soerens AG, Wijeyesinghe SP, Beura LK, Dileepan G, Burbach BJ, Künzli M, Quarnstrom CF, Ghirardelli Smith OC, Weyu E, Hamilton SE, Vezys V, Shalek AK, Masopust D. Immunity. 2025 Jan 14;58(1):162-181.e10. doi: 10.1016/j.immuni.2024.11.007. Epub 2024 Dec 20.
PMID: 39708817

Bajaj JS, Fagan A, Gavis EA, Sterling RK, Gallagher ML, Lee H, Matherly SC, Siddiqui MS, Bartels A, Mousel T, Davis BC, Puri P, Fuchs M, Moutsoglou DM, Thacker LR, Sikaroodi M, Gillevet PM, Khoruts A.
J Hepatol. 2025 Jan 10:S0168-8278(25)00005-4. doi: 10.1016/j.jhep.2024.12.047. Online ahead of print.
PMID: 39800192

Protocol for applying Tumor Treating Fields in mouse models of cancer using the inovivo system.

Gates TJ, Zbidat S, Deniz K, Padmanabhan S, Ladner K, Sarkari A, Zhao X, Davidi S, Blatt R, Cahal S, Gabay M, Sellevoll M, Tzchori I, Porat Y, Haber A, Giladi M, Subramanian S, Lou E.
STAR Protoc. 2025 Jan 8;6(1):103535. doi: 10.1016/j.xpro.2024.103535. Online ahead of print.
PMID: 39792561

Implantation of Islets Co-Seeded with Tregs in a Novel Biomaterial Reverses Diabetes in the NOD Mouse Model.

Elizondo DM, de Oliveira Rekowsky LL, de Sa Resende A, Seenarine J, da Silva RLL, Ali J, Yang D, de Moura T, Lipscomb MW.
Tissue Eng Regen Med. 2025 Jan;22(1):43-55. doi: 10.1007/s13770-024-00685-7. Epub 2024 Dec 30.
PMID: 39738937