2026 Publications
Nat Immunol. 2026 Aug;27(8):1708-1721. doi: 10.1038/s41590-026-02581-9.
PMID: 42399696
Mol Pharm. 2026 Aug 3;23(8):4079-4088. doi: 10.1021/acs.molpharmaceut.5c01902.
PMID: 42391610
Case of complete response to immunotherapy in MMR-deficient prostate cancer associated with NK-like and CD4+CD8+ T cells. External link that opens in the same window
Tsai AK, Lozada JR, Kennedy PR, Moline D, Pandey R, Lyons RC, Luo C, Wang R, Arafa AT, Femino EL, Zipkowitz S, Figueroa A, McCann PJ, Dallos MC, Elliott A, Murugan P, Felices M, Zorko NA, Konety BR, Dehm SM, Miller JS, Shen SS, Thompson EA, Sena LA, Yegnasubramanian S, Hwang J, Antonarakis ES.
Cell Rep Med. 2026 Jul 21;7(7):102889. doi: 10.1016/j.xcrm.2026.102889. Epub 2026 Jun 26.
PMID: 42361800
Weingarden AR, Dahlberg FS, Broude CN, Meng X, Jain S, Weakley AM, Cabrera AV, Dileepan T, Fischbach MA, Jenkins MK.
J Immunol. 2026 Jul 10;215(7):vkag172. doi: 10.1093/jimmun/vkag172.
PMID: 42533363
Dixon KJ, Walcheck B.
Cells. 2026 Jul 15;15(14):1269. doi: 10.3390/cells15141269.
PMID: 42505378
Sommer AJ, Loon E, Khoruts A, Aby ES.
J Crohns Colitis. 2026 Jul 7;20(7):jjag099. doi: 10.1093/ecco-jcc/jjag099.
PMID: 42490468
A Singular Base Editing Platform for Polyfunctional Multiplex Engineering of Immune Cells.External link that opens in the same window
Skeate JG, Slipek NJ, Lahr WS, Roy S, Wick BJ, Kar B, Chang JW, Stelljes EM, Gilkey AK, Thenge PP, Diers MD, Krueger JB, Niemeyer EM, Lonetree CL, Kluesner MG, Bell JB, Clement K, Provenzano PP, Moriarity BS, Webber BR.
Mol Ther. 2026 Jul 17:S1525-0016(26)00601-5. doi: 10.1016/j.ymthe.2026.07.033. Online ahead of print.
PMID: 42470099
Martinez RJ, Rivera-León AM, Nikolaeva A, Esposito K, Vobořil M, Boorsma Bergerud K, Arroyo M, Nelson AC, Farrar MA, Tracy SI, Reboldi A, Fife BT, Hogquist KA.
J Immunol. 2026 Jul 10;215(7):vkag185. doi: 10.1093/jimmun/vkag185.
PMID: 42464563
Lee CJ, Larsson AT, Jubenville TA, Hudson WA, Seeman ZJ, Stewart C, Tsai AK, Burrack A, Kimball BL, Siegler EL, Vianzon VV, Nolan EE, Yang YL, Stehn CM, Gohl DM, Donovan M, Temiz NA, Popescu FE, Warming S, Seshagiri S, You Y, Riordan JD, Dupuy A, Moriarity B, Rogers L, Stromnes I, Kenderian S, Largaespada D.
J Immunother Cancer. 2026 Jul 15;14(7):e013536. doi: 10.1136/jitc-2025-013536.
PMID: 42457339
J Immunol. 2026 Jul 10;215(7):vkag174. doi: 10.1093/jimmun/vkag174.
PMID: 42441427
NK cell immunotherapy after analytic treatment interruption is associated with HIV viral control.External link that opens in the same window
Thron LK, Pumtang-On P, Chang JW, Cantor ME, Gorrell-Brown I, Becklin KL, Quinn ZE, Karim AF, Rendahl AK, Pampusch MS, Casares SA, Vezys V, Moriarity BS, Skinner PJ.
Mol Ther Adv. 2026 Jun 11;34(3):201778. doi: 10.1016/j.omta.2026.201778. eCollection 2026 Sep 10.
PMID: 42422767
CSF1R regulates monocyte subset differentiation and intracellular metabolism. External link that opens in the same window
Gallerand A, Merlin J, Caillot Z, Delaby C, Bord E, Han J, Dolfi B, Chang MD, Thierry GR, Castiglione A, Grenet S, Goës E, Franceschini M, Jarretou G, Zair FN, Boré E, Tuffin F, Dombrowicz D, Chinetti G, Guinamard RR, Artyomov MN, Wakkach A, Pisani DF, Randolph GJ, Bertola A, Auberger P, Jacquel A, Hume DA, Williams JW, Bajénoff M, Neels JG, Ivanov S.
Nat Commun. 2026 Jul 4. doi: 10.1038/s41467-026-75263-7. Online ahead of print.
PMID: 42401537
Myeloid Piezo1 as a Brake on Efferocytosis and Cardiac Repair in the Infarcted Heart. External link that opens in the same window
Hakeem A, Revelo XS.
Circ Res. 2026 Jul 6;139(2):e328984. doi: 10.1161/CIRCRESAHA.126.328984. Epub 2026 Jul 2.
PMID: 42391320
CD69 Regulates Gingival Inflammation and Microbiome in Periodontitis. External link that opens in the same window
Saavedra FM, Fischer L, Bittner-Eddy PD, Johnstone KF, Stolley JM, Williams DW, Herzberg MC, Costalonga M.
J Dent Res. 2026 Jul;105(7):930-937. doi: 10.1177/00220345251383827. Epub 2025 Nov 26.
PMID: 41299866
Treg cells promote immunotherapy-induced immune evasion by restraining CD4 T cell control of MHC-I-deficient metastatic pancreatic cancer.External link that opens in the same window
Schmiechen ZC, Cruz-Hinojoza E, Hilk AL, Ellefson MA, Tsai AK, Dres OM, Kang LI, Geuenich MJ, Butler JZ, Burrack AL, Larsen BM, Hickok GH, Miller EA, Lonetree CL, Gaire A, Pandey R, Nanda HA, Chaudhury I, Corbiere T, Dileepan T, Shen SS, Campbell KR, DeNardo DG, Stromnes IM.
Sci Immunol. 2026 Jun 26;11(120):eadz4302. doi: 10.1126/sciimmunol.adz4302. Epub 2026 Jun 26.
PMID: 42361199
Distinct immune trajectories after severe trauma identify a Th17-biased immunophenotype in chronic critical illness.External link that opens in the same window
Kim CY, Ding H, Mirabadi N, Luo S, Scherler K, Walters KA, O'Keefe G, Griffith TS, Brakenridge SC.
J Immunol. 2026 Jun 7;215(6):vkag125. doi: 10.1093/jimmun/vkag125.
PMID: 42343164
Adrenal Gland Macrophage-derived TGF-β Governs Vascular Permeability to Drive Monocyte Recruitment during Stress.External link that opens in the same window
Xu Y, Patterson MT, Chang MD, Ahlberg I, Liu CY, Roll C, Hillman H, Kennedy A, Schrank PR, Stuttgen GM, Kubota Y, Ivanov S, Binstadt BA, Williams JW.
bioRxiv [Preprint]. 2026 May 21:2026.05.18.726080. doi: 10.64898/2026.05.18.726080.
PMID: 42239159
Effective macrophage clearance of Klebsiella pneumoniae requires the inducible nitric oxide synthase iNOS and is independent of reactive oxygen species generated by NADPH oxidase.External link that opens in the same window
Wilcox AE, Andres CJ, Madigan EH, Olive AJ, Holmes CL.
bioRxiv [Preprint]. 2026 May 18:2026.05.14.724925. doi: 10.64898/2026.05.14.724925.
PMID: 42239106
Silva Morales M, Mueller DL.
J Immunol. 2026 May 14;215(5):vkag097. doi: 10.1093/jimmun/vkag097.
PMID: 42153446
Krüppel-like factors 2 and 3 regulate T cell exhaustion by directing T cell residency and migration.External link that opens in the same window
Shen J, Brown RJ, Zhang Y, Gai K, Brown AK, Bauer AM, Zhu A, Lin S, Niu H, Kharel A, Xu Z, Cohen GS, Depauw TA, Fagerberg E, Kansas GS, Joshi NS, Jameson SC, Cui W.
Immunity. 2026 May 12;59(5):1287-1305.e7. doi: 10.1016/j.immuni.2026.02.021. Epub 2026 Mar 27.
PMID: 41903548
Wilt AL, Meya DB, Cresswell FV, Wele A, Kabahubya M, Kagimu E, Gakuru J, Mugabi T, Kimuda S, Namombwe S, Tukundane A, Okafor EC, Okurut S, Scriven JE, Dai B, Engen N, Bahr NC, Boulware DR, Bold TD.
J Infect Dis. 2026 Apr 29;233(4):787-798. doi: 10.1093/infdis/jiag032.
PMID: 41527237
Complement 3a Receptor mediates high fat diet induced hypothalamic accumulation of lipid associated microglia to regulate neuroinflammation and obesity.External link that opens in the same window
Pallais JP, Razzoli M, Rodriguez P, McGonigle S, Daugherty A, Hillman H, Verteramo L, Schrank PR, Parthiban P, Chang X, Wang H, Veglia G, Köhl J, Bose M, Ehrlich ME, Salton SRJ, Araque A, Barbato DL, Revelo XS, Ruan HB, Williams JW, Bartolomucci A.
bioRxiv [Preprint]. 2026 Apr 22:2026.04.18.719397. doi: 10.64898/2026.04.18.719397.
PMID: 42079094
Sci Transl Med. 2026 Apr 22;18(846):eaef8756. doi: 10.1126/scitranslmed.aef8756.
PMID: 42018667
Front Immunol. 2026 Apr 23;17:1846400. doi: 10.3389/fimmu.2026.1846400. eCollection 2026.
PMID: 42112368
J Lipid Res. 2026 Apr 16:101041. doi: 10.1016/j.jlr.2026.101041. Online ahead of print.
PMID: 41999980
Infect Immun. 2026 Apr 15;94(4):e0073925. doi: 10.1128/iai.00739-25. Epub 2026 Feb 23.
PMID: 41728977
Jameson SC, Hamilton SE.
Immunity. 2026 Apr 14;59(4):847-862. doi: 10.1016/j.immuni.2026.03.014.
PMID: 41985442
Bone marrow and splenic immune composition is unperturbed by short-term exposure to bedding from pet store mice.External link that opens in the same window
Little-Letsinger SE, Karmaus PWF, Fessler MB, Hamilton SE.
Immunohorizons. 2026 Apr 11;10(4):vlag014. doi: 10.1093/immhor/vlag014.
PMID: 41968728
An immunobiliary single-cell atlas resolves crosstalk between type 2 conventional dendritic cells and γδ T cells in cholangitis.External link that opens in the same window
Thomann S, Hemmer H, Agrawal A, Basu S, Schaf J, Vornberger N, Krammer T, Sagar, Imdahl F, Poth T, Tóth M, Zielinski CE, Poch T, Krause J, Rosenwald A, Breitkopf-Heinlein K, Rahbari N, Grün D.
Nat Commun. 2026 Apr 10;17(1):3455. doi: 10.1038/s41467-026-71537-2.
PMID: 41963321
Immunotherapy with Guts: A review of microbial therapeutic adjuncts for immunotherapy in solid tumors. External link that opens in the same window
Pum K, Lou E, Goffredo P, Jahansouz C, Subramanian S, Prakash A.
Oncologist. 2026 Apr 9:oyag131. doi: 10.1093/oncolo/oyag131. Online ahead of print.
PMID: 41967083
Fecal Microbiota Transplantation Rapidly Reduces Systemic Inflammation and Resolves C. difficile Pseudomembranous Colitis.External link that opens in the same window
Khoruts A, Kuchma N, Vaughn BP.
Clin Gastroenterol Hepatol. 2026 Apr 6:S1542-3565(26)00233-8. doi: 10.1016/j.cgh.2026.03.023. Online ahead of print.
PMID: 41950979
Guidelines for T cell nomenclature.External link that opens in the same window
Masopust D, Awasthi A, Bosselut R, Brooks DG, Buggert M, Chamoto K, Cui W, Dong C, Farber DL, Gebhardt T, Gerlach C, Goldrath A, Greenberg PD, Hale JS, Hayday A, Homann D, Iannacone M, Jameson SC, Jenkins MK, Joshi NS, Kaech SM, Kallies A, Kamphorst AO, Kaplan MH, Klenerman P, Künzli M, Lanzavecchia A, Lauer GM, Lugli E, Luster AD, Mackay LK, McElrath MJ, Mueller SN, Ndhlovu Z, Ndung'u T, Ohashi PS, Oxenius A, Pantaleo G, Pepper M, Picker LJ, Quarnstrom CF, Reyes-Terán G, Roederer M, Rosato PC, de Oca GS, Sallusto F, Schumacher TN, Schwartz DM, Shin EC, Soerens AG, Thommen DS, Vezys V, Viola JPB, Walker BD, Watts TH, Weaver CT, Wherry EJ, Xue HH, Youngblood B, Ahmed R.
Nat Rev Immunol. 2026 Apr;26(4):298-313. doi: 10.1038/s41577-025-01238-2. Epub 2025 Nov 18.
PMID: 41254224
KLF2 overrides the resident memory CD8 T cell differentiation program, in opposition to KLF3.External link that opens in the same window
DePauw TA, Gai K, Shen J, Maurice NJ, Rhee KH, Valente WJ, O'Connor CH, Cui W, Peng C, Jameson SC.
Proc Natl Acad Sci U S A. 2026 Mar 31;123(13):e2533700123. doi: 10.1073/pnas.2533700123. Epub 2026 Mar 23.
PMID: 41871244
Perinatal microbial exposure and the shaping of the early immune system: lessons from experimental modelsExternal link that opens in the same window.
Smith P, Whillock A, Schuldt NJ.
Curr Opin Physiol. 2026 Mar;47:100911. doi: 10.1016/j.cophys.2026.100911. Epub 2026 Feb 16.
PMID: 41858419
Yang X, Colden MA, Coombs R, Arana K, Tran D, Valerio MM, Robey EA, Coscoy L.
Eur J Immunol. 2026 Mar;56(3):e70161. doi: 10.1002/eji.70161.
PMID: 41817308
J Exp Med. 2026 Mar 2;223(3):e20251962. doi: 10.1084/jem.20251962.
PMID: 41348320
Maurice NJ, Dalzell TS, Tankersley TN, Rhee KH, Block KE, Jarjour NN, DePauw TA, Wall SM, Hamilton SE, Jameson SC.
Nat Immunol. 2026 Mar;27(3):476-489. doi: 10.1038/s41590-026-02430-9. Epub 2026 Feb 10.
PMID: 41667619
Proximity-ligation metagenomics reveals disease-specific mobilome dynamics in disrupted gut ecosystems.External link that opens in the same window
Sommer AJ, Auch B, Khoruts A, Bajaj JS.
Res Sq [Preprint]. 2026 Mar 25:rs.3.rs-9142184. doi: 10.21203/rs.3.rs-9142184/v1.
PMID: 41928791
Basal phosphorylation of SHIP1 by Lyn suppresses proinflammatory signaling in the absence of a phagocytic synapse. External link that opens in the same window
Senevirathne SE, Kanagy WK, Hemmila CR, Greene JT, Rajczewski AT, Cattley RT, Swanson WL, Toledo Ramos S, Nunez MG, Jin S, Hawse WF, Freedman TS.
J Immunol. 2026 Mar 17;215(3):vkaf372. doi: 10.1093/jimmun/vkaf372.
PMID: 41916428
STEVE: Single-cell Transcriptomics Expression Visualization and Evaluation.External link that opens in the same window
Torbenson E, Ma X, Lin JR, Garry DJ, Jameson SC, Zhang Z, Niedernhofer LJ, Zhang L, Li M, Dong X.
bioRxiv [Preprint]. 2026 Mar 13:2026.03.10.710898. doi: 10.64898/2026.03.10.710898.
PMID: 41959208
Strengths and limitations of in vitro and animal models to advance understanding of human diet‒microbiome interactions.External link that opens in the same window
Weingarden AR.
Gut Microbes Rep. 2026 Mar 3;3(1):2636336. doi: 10.1080/29933935.2026.2636336. eCollection 2026.
PMID: 41918983
Perinatal microbial exposure and the shaping of the early immune system: lessons from experimental modelsExternal link that opens in the same window
Smith P, Whillock A, Schuldt NJ.
Curr Opin Physiol. 2026 Mar;47:100911. doi: 10.1016/j.cophys.2026.100911. Epub 2026 Feb 16.
PMID: 41858419
Non-cognate CD8 Binding to MHC I Promotes Positive Selection of an MHC-E Restricted CD8 T Cell Population.External link that opens in the same window
Yang X, Colden MA, Coombs R, Arana K, Tran D, Valerio MM, Robey EA, Coscoy L.
Eur J Immunol. 2026 Mar;56(3):e70161. doi: 10.1002/eji.70161.
PMID: 41817308
Quantifying Nuance Within Sepsis-Associated Immune Suppression Toward Diagnostic Certainty. External link that opens in the same window
Caldwell CC, Maile R, Mazer MB, McGonagill PW, Bergmann CB, Gould RW, Rao M, Hernández-Ríos M, Ungaro RF, Loftus TJ, Efron PA, Remy KE, Brakenridge SC, Badovinac VP, Griffith TS, Hotchkiss RS, Moldawer LL.
Shock. 2026 Mar 1;65(3):555-559. doi: 10.1097/SHK.0000000000002745.
PMID: 41166166
CXCL10 Regulates Pressure Overload-Induced Heart Failure. External link that opens in the same window
Souza-Neto F, Le P, Abdrabbo M, Alamgir A, Wang H, Ferreira de Araujo N, Mikkila JL, Sanches B, Parthiban P, Moon R, Herman A, Adams AB, Prins KW, Guatimosim S, Schuldt N, Revelo XS, van Berlo JH.
JACC Basic Transl Sci. 2026 Mar;11(3):101462. doi: 10.1016/j.jacbts.2025.101462.
PMID: 42018138
Jang IH, Niedernhofer LJ, Robbins PD, Camell CD.
Nat Rev Immunol. 2026 Feb 13. doi: 10.1038/s41577-026-01269-3. Online ahead of print.
PMID: 41688787
Distinct spatial organization governs oral mucosal immunity. External link that opens in the same window
Theofilou VI, Fraser D, Kanasi E, Brenchley L, Greenwell-Wild T, Adade EE, Valm AM, Douagi I, Belkaid Y, Tran DT, Williams DW, Moutsopoulos NM.
Nat Immunol. 2026 Feb 9. doi: 10.1038/s41590-025-02398-y. Online ahead of print.
PMID: 41663813
Diverse Microbial Exposure Enhances CD8+ T Cell Effector Memory Output and Function.External link that opens in the same window
Thefaine CE, Lucas ED, Block KE, Pierson M, Dehm EM, Huggins MA, Casey OW, Zemmour D, Jameson SC, Hamilton SE; immgenT Project.
bioRxiv [Preprint]. 2026 Feb 4:2026.02.02.703037. doi: 10.64898/2026.02.02.703037.
PMID: 41676686
Am J Reprod Immunol. 2026 Feb;95(2):e70213. doi: 10.1111/aji.70213.
PMID: 41618722
Dual-functioning Targeted ADAM17 Blocker CD16 (TAB16) mediates selective ADAM17 inhibition in NK cells and engages overexpressed ADAM17 in tumor cells to induce cytotoxicity.External link that opens in the same window
Dixon KJ, Hullsiek R, Wang S, Friess RR, Matson AW, Soignier Y, Lenvik AJ, Wu J, Hart GT, Felices M, Walcheck B.
Front Immunol. 2026 Jan 30;17:1714022. doi: 10.3389/fimmu.2026.1714022. eCollection 2026.
PMID: 41694365
When Smell Drives Swell: Olfr2 Fuels Inflammation in AAA. External link that opens in the same window
Stuttgen GM, Chang M, Williams JW.
Circ Res. 2026 Jan 30;138(3):e327969. doi: 10.1161/CIRCRESAHA.125.327969. Epub 2026 Jan 29.
PMID: 41610191
Ongoing lymphoid HIV production drives pyroptosis and GLP-1 counter-regulation in ART-suppressed infection.External link that opens in the same window
Crawford PA, Rhein J, Chipman JG, Beilman GJ, Cromarty R, Escandón K, Anderson J, Wieking G, Johnston A, Ahmed A, Reichel J, Khoruts A, Basting CM, Kuchma N, Baker JV, Klatt NR, Haase AT, Schacker TW.
bioRxiv [Preprint]. 2026 Jan 10:2026.01.09.698696. doi: 10.64898/2026.01.09.698696.
PMID: 41542439
Toll-Like Receptor 7/8 Antagonist Promotes Interleukin-10-Mediated Anti-inflammatory Therapy.External link that opens in the same window
Funk GA, Xie J, Kucaba TA, Griffith TS, Ferguson DM, Kim H.
ACS Pharmacol Transl Sci. 2025 Dec 11;9(1):114-125. doi: 10.1021/acsptsci.5c00604. eCollection 2026 Jan 9.
PMID: 41536275
A host-adapted commensal fungus from pet store mice drives type 2 immunity and cross-kingdom protection. External link that opens in the same window
Han G, Yunker R, Hasan MH, Bruce A, Baldaro K, Pacia J, Jarjour NN, Beura LK, Vaishnava S.
bioRxiv [Preprint]. 2026 Jan 6:2025.04.30.651489. doi: 10.1101/2025.04.30.651489.
PMID: 41542591
Intrinsic OASL expression governs heterogeneity in interferon induction during influenza A virus infection.External link that opens in the same window
Rivera-Cardona J, Mahajan T, Thayer EA, Kakuturu NR, Teo QW, Lederer J, Rowland EF, Heimburger K, Sun J, McDonald CA, Mickelson CK, Langlois RA, Wu NC, Milenkovic O, Maslov S, Brooke CB.
Proc Natl Acad Sci U S A. 2026 Jan 6;123(1):e2509560123. doi: 10.1073/pnas.2509560123.
PMID: 41468430
Altered natural killer cell function in children with severe malariaExternal link that opens in the same window.
Turyasingura G, Mellencamp KA, Namazzi R, Opoka RO, John CC, Hart GT.
Immunohorizons. 2026 Jan 6;10(1):vlaf070. doi: 10.1093/immhor/vlaf070.
PMID: 41491654
Thymic myeloid cells are heterogenous and include a novel population of transitional dendritic cells.External link that opens in the same window
Vobořil M, Sulczewski FB, Martinez RJ, Ashby KM, Valerio MM, Idoyaga J, Hogquist KA.
J Exp Med. 2026 Jan 5;223(1):e20250733. doi: 10.1084/jem.20250733. Epub 2025 Oct 22.
PMID: 41123595
J Immunother. 2026 Jan 1;49(1):1-14. doi: 10.1097/CJI.0000000000000571.
PMID: 40765175