Fellowship dates: 1993-1996
Research Emphasis:  Use of a beta1 integrin-deficient human T cell to identify beta1 integrin cytoplasmic domain sequences critical for integrin function., T-lymphocyte interactions with endothelium and extracellular matrix.

Fellowship dates: 1999-2002
Research Emphasis: Control of TCR-mediated activation of beta 1 integrins by the ZAP-70 tyrosine kinase interdomain B region and the linker for activation of T cells adapter protein.

Current Position: Assistant Professor, Department of Biochemistry, Osaka Dental University, Osaka, Japan
Contact: [email protected] 

Fellowship dates: 2011-2013
Research Emphasis: ICAM-1-dependent homotypic aggregates regulate CD8 T cell effector function and differentiation during T cell activation.

Current Position: Department of Biochemistry, Osaka Dental University, Osaka, Japan
Contact: [email protected]  

Fellowship dates: 1999-2004
Research Emphasis:  Measured effect of kinase-dead or dominant negative PKC constructs on static adhesion of T cells. Determined localization of PKCmu in response to stimulation by confocal microscopy. Isolation of PKCmu binding partners by immunoprecipitation and Western blotting.

Fellowship dates: 2002-2006
Advisor: Yoji Shimizu
Research Emphasis:  Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1., Protein kinase D1 and the beta 1 integrin cytoplasmic domain control beta 1 integrin function via regulation of Rap1 activation.

Fellowship dates: 1998-2000
Research Emphasis: Regulation of beta 1 integrin-mediated adhesion by T cell receptor signaling involves ZAP-70 but differs from signaling events that regulate transcriptional activity., Protein kinase D1 and the beta 1 integrin cytoplasmic domain control beta 1 integrin function via regulation of Rap1 activation.

Fellowship dates: 1998-1999
Research Emphasis:  Cutting edge: T cell migration regulated by CXCR4 chemokine receptor signaling to ZAP-70 tyrosine kinase.

Current Position: Senior Scientist, HiberCell, Roseville, MN
Contact Info: achan@hibercell.com

Contact Info: [email protected] 

Current:
Senior Research Associate: 2009-present
Mentor: Yoji Shimizu (Lab website)
Research Emphasis/Publications: Activation and distribution of tumor-specific T cells. Full list of Publications

Fellowship dates: 1996-2000
Research Emphasis:  Stimulation of beta1-integrin function by epidermal growth factor and heregulin-beta has distinct requirements for erbB2 but a similar dependence on phosphoinositide 3-OH kinase.

Fellowship dates: 1993-1995
Advisor: Matthew Mescher
Research Emphasis:

Research Associate: 1999-2003
Advisor: Yoji Shimizu
Research Emphasis/Publications:

Current Position: Homemaker, Minneapolis, MN
Contact Info: [email protected]