Fellowship dates: 1995-1999
Research Emphasis: Identification of a proline-rich sequence in the CD2 cytoplasmic domain critical for regulation of integrin-mediated adhesion and activation of phosphoinositide 3-kinase.
Fellowship dates: 1999-2002
Research Emphasis: Control of TCR-mediated activation of beta 1 integrins by the ZAP-70 tyrosine kinase interdomain B region and the linker for activation of T cells adapter protein.
Current Position: Assistant Professor, Department of Biochemistry, Osaka Dental University, Osaka, Japan
Contact: [email protected]
Fellowship dates: 2011-2013
Research Emphasis: ICAM-1-dependent homotypic aggregates regulate CD8 T cell effector function and differentiation during T cell activation.
Current Position: Department of Biochemistry, Osaka Dental University, Osaka, Japan
Contact: [email protected]
Fellowship dates: 1999-2004
Research Emphasis: Measured effect of kinase-dead or dominant negative PKC constructs on static adhesion of T cells. Determined localization of PKCmu in response to stimulation by confocal microscopy. Isolation of PKCmu binding partners by immunoprecipitation and Western blotting.
Fellowship dates: 1998-2000
Research Emphasis: Regulation of beta 1 integrin-mediated adhesion by T cell receptor signaling involves ZAP-70 but differs from signaling events that regulate transcriptional activity., Protein kinase D1 and the beta 1 integrin cytoplasmic domain control beta 1 integrin function via regulation of Rap1 activation.
Fellowship dates: 1998-1999
Research Emphasis: Cutting edge: T cell migration regulated by CXCR4 chemokine receptor signaling to ZAP-70 tyrosine kinase.
Current Position: Senior Scientist, HiberCell, Roseville, MN
Contact Info: achan@hibercell.com
Contact Info: [email protected]
Current:
Senior Research Associate: 2009-present
Mentor: Yoji Shimizu (Lab website)
Research Emphasis/Publications: Activation and distribution of tumor-specific T cells. Full list of Publications
Fellowship dates: 1996-2000
Research Emphasis: Stimulation of beta1-integrin function by epidermal growth factor and heregulin-beta has distinct requirements for erbB2 but a similar dependence on phosphoinositide 3-OH kinase.
Fellowship dates: 2017-2021
Research Emphasis: Tumor immunology and radio-immunotherapy.
Current Position: Radiation Oncologist, Allegheny Health Network St. Vincent, Erie, PA
Contact Info: [email protected]
