2020 publications
Monocyte Recruitment, Specification, and Function in Atherosclerosis.
Cells. 2020 Dec 24;10(1):E15. doi: 10.3390/cells10010015.
PMID: 33374145
Probiotics and the Microbiome: How can we help patients make sense of probiotics?
Gastroenterology. 2020 Dec 8:S0016-5085(20)35525-6. doi: 10.1053/j.gastro.2020.11.047.
PMID: 33307023
Monoclonal Antibodies Counteract Opioid-Induced Behavioral and Toxic Effects in Mice and Rats.
J Pharmacol Exp Ther. 2020 Dec;375(3):469-477. doi: 10.1124/jpet.120.000124. Epub 2020 Sep 26.
PMID: 32980813
Curr Protoc Immunol. 2020 Dec;131(1):e110. doi: 10.1002/cpim.110.
PMID: 33027848
Methanogen Abundance Thresholds Capable of Differentiating In Vitro Methane Production in Human Stool Samples.
Dig Dis Sci. 2020 Nov 28. doi: 10.1007/s10620-020-06721-5.
PMID: 33247793
Therapeutic and Prophylactic Vaccines to Counteract Fentanyl Use Disorders and Toxicity.
J Med Chem. 2020 Nov 20. doi: 10.1021/acs.jmedchem.0c01042.
PMID: 33215913
Sepsis impedes EAE disease development and diminishes autoantigen-specific naïve CD4 T cells.
Elife. 2020 Nov 16;9:e55800. doi: 10.7554/eLife.55800.
PMID: 33191915
Competition for Active TGFβ Cytokine Allows for Selective Retention of Antigen-Specific Tissue- Resident Memory T Cells in the Epidermal Niche.
Immunity. 2020 Nov 11:S1074-7613(20)30463-5. doi: 10.1016/j.immuni.2020.10.022.
PMID: 33212014
T cell economics: precursor cells predict inflation.
Nat Immunol. 2020 Oct 29. doi: 10.1038/s41590-020-00819-8. Online ahead of print.
PMID: 33122851
Comparative analysis of genome-wide DNA methylation identifies patterns that associate with conserved transcriptional programs in osteosarcoma.
Bone. 2020 Oct 27:115716. doi: 10.1016/j.bone.2020.115716.
PMID: 33127576
Countermeasures for preventing and treating opioid overdose.
Clin Pharmacol Ther. 2020 Oct 28. doi: 10.1002/cpt.2098.
PMID: 33113208
T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis.
Nat Commun. 2020 Oct 26;11(1):5406. doi: 10.1038/s41467-020-18961-0.
PMID: 33106495
Repeated dermal application of the common preservative methylisothiazolinone triggers local inflammation, T cell influx, and prolonged mast cell-dependent tactile sensitivity in mice.
PLoS One. 2020 Oct 26;15(10):e0241218. doi: 10.1371/journal.pone.0241218. eCollection 2020.
PMID: 33104726
Mechanisms of interleukin 4 mediated increase in efficacy of vaccines against opioid use disorders.
NPJ Vaccines. 2020 Oct 21;5:99. doi: 10.1038/s41541-020-00247-7. eCollection 2020.
PMID: 33101712
Single Cell resolution of SARS-CoV-2 tropism, antiviral responses, and susceptibility to therapies in primary human airway epithelium
bioRxiv. 2020 Oct 19:2020.10.19.343954. doi: 10.1101/2020.10.19.343954. Preprint.
PMID: 33106802
Anti-Inflammatory and Proresolving Effects of the Omega-6 Polyunsaturated Fatty Acid Adrenic Acid.
J Immunol. 2020 Oct 2:ji1801653. doi: 10.4049/jimmunol.1801653.
PMID: 33008950
Cerebrospinal fluid bacillary load by Xpert MTB/RIF Ultra PCR Cycle Threshold value predicts two-week mortality in HIV-associated tuberculous meningitis.
Clin Infect Dis. 2020 Sep 28:ciaa1444. doi: 10.1093/cid/ciaa1444.
PMID: 32986792
Diverse Macrophage Populations Contribute to the Inflammatory Microenvironment in Premalignant Lesions During Localized Invasion.
Front Oncol. 2020 Sep 24;10:569985. doi: 10.3389/fonc.2020.569985. eCollection 2020.
PMID: 33072601
Hybrid Fc-fused interleukin-7 induces an inflamed tumor microenvironment and improves the efficacy of cancer immunotherapy.
Clin Transl Immunology. 2020 Sep 4;9(9):e1168. doi: 10.1002/cti2.1168. eCollection 2020.
PMID: 32994996
Antigen-Specific CD4+ T Cells Exhibit Distinct Kinetic and Phenotypic Patterns During Primary and Secondary Responses to Infection.
Front Immunol. 2020 Sep 2;11:2125. doi: 10.3389/fimmu.2020.02125. eCollection 2020.
PMID: 32983171
SARS-CoV-2 neutralization and serology testing of COVID-19 convalescent plasma from donors with non-severe disease.
Transfusion. 2020 Sep 16. doi: 10.1111/trf.16101.
PMID: 32935872
Immunopharmacology and Quantitative Analysis of Tyrosine Kinase Signaling.
Curr Protoc Immunol. 2020 Sep;130(1):e104. doi: 10.1002/cpim.104.
PMID: 32931655
The relationship between CD4+ follicular helper T cells and CD8+ resident memory T cells: sisters or distant cousins?
Int Immunol. 2020 Sep 8;32(9):583-587. doi: 10.1093/intimm/dxaa045.
PMID: 32620009
Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression.
Nat Immunol. 2020 Sep 7. doi: 10.1038/s41590-020-0768-4.
PMID: 32895539
Lessons of COVID-19: A roadmap for post-pandemic science.
J Exp Med. 2020 Sep 7;217(9):e20201276. doi: 10.1084/jem.20201276.
PMID: 32735669
P2Y11: The CD4 T cell mitochondrial shepherd.
J Leukoc Biol. 2020 Sep 2. doi: 10.1002/JLB.2CE0620-240R.
PMID: 32876961
Isolation of Cancer-Derived Exosomes Using a Variety of Magnetic Nanostructures: From Fe3O4 Nanoparticles to Ni Nanowires.
Nanomaterials (Basel). 2020 Aug 25;10(9):E1662. doi: 10.3390/nano10091662.
PMID: 32854239
Faecal microbiota transplantation for Clostridioides difficile: mechanisms and pharmacology.
Nat Rev Gastroenterol Hepatol. 2020 Aug 25. doi: 10.1038/s41575-020-0350-4.
PMID: 32843743
ZipSeq: barcoding for real-time mapping of single cell transcriptomes.
Nat Methods. 2020 Aug;17(8):833-843. doi: 10.1038/s41592-020-0880-2. Epub 2020 Jul 6.
PMID: 32632238
Cell type- and replication stage-specific influenza virus responses in vivo.
PLoS Pathog. 2020 Aug 13;16(8):e1008760. doi: 10.1371/journal.ppat.1008760.
PMID: 32790753
Polymicrobial Sepsis Impairs Antigen-Specific Memory CD4 T Cell-Mediated Immunity.Polymicrobial Sepsis Impairs Antigen-Specific Memory CD4 T Cell-Mediated Immunity.
Front Immunol. 2020 Aug 12;11:1786. doi: 10.3389/fimmu.2020.01786. eCollection 2020.
PMID: 32903436
Protein O-GlcNAc Modification Links Dietary and Gut Microbial Cues to the Differentiation of Enteroendocrine L Cells.
Cell Rep. 2020 Aug 11;32(6):108013. doi: 10.1016/j.celrep.2020.108013.
PMID: 32783937
Novel protein pathways in development and progression of pulmonary sarcoidosis.
Sci Rep. 2020 Aug 6;10(1):13282. doi: 10.1038/s41598-020-69281-8.
PMID: 32764642
Intestinal CD8αα IELs derived from two distinct thymic precursors have staggered ontogeny.
J Exp Med. 2020 Aug 3;217(8):e20192336. doi: 10.1084/jem.20192336
PMID: 32687575
Retrograde migration supplies resident memory T cells to lung-draining LN after influenza infection.
J Exp Med. 2020 Aug 3;217(8):e20192197. doi: 10.1084/jem.20192197.
PMID: 32568362
Adoptive T Cell Therapy with IL-12-Preconditioned Low-Avidity T Cells Prevents Exhaustion and Results in Enhanced T Cell Activation, Enhanced Tumor Clearance, and Decreased Risk for Autoimmunity.
J Immunol. 2020 Jul 31:ji2000007. doi: 10.4049/jimmunol.2000007.
PMID: 32737148
Kinetically distinct processing pathways diversify the CD8+ T cell response to a single viral epitope.
Proc Natl Acad Sci U S A. 2020 Jul 27:202004372. doi: 10.1073/pnas.2004372117.
PMID: 32719124
Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas.
Circ Res. 2020 Jul 17;127(3):402-426. doi: 10.1161/CIRCRESAHA.120.316903. Epub 2020 Jul 16.
PMID: 32673538
CD4 T Cell Responses and the Sepsis-Induced Immunoparalysis State.
Front Immunol. 2020 Jul 7;11:1364. doi: 10.3389/fimmu.2020.01364. eCollection 2020.
PMID: 32733454
Chemotherapy brings virtual memory T cells into reality for cancer therapy.
Cell Mol Immunol. 2020 Jul 3. doi: 10.1038/s41423-020-0496-6.
PMID: 32620786
Sensing of ATP via the Purinergic Receptor P2RX7 Promotes CD8+ Trm Cell Generation by Enhancing Their Sensitivity to the Cytokine TGF-β.
Immunity. 2020 Jul 2:S1074-7613(20)30265-X. doi: 10.1016/j.immuni.2020.06.010.
PMID: 32640257
Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function.
PLoS One. 2020 Jul 2;15(7):e0235518. doi: 10.1371/journal.pone.0235518. eCollection 2020.
PMID: 32614928
KLRG1+ Memory CD8 T Cells Combine Properties of Short-Lived Effectors and Long-Lived Memory.
J Immunol. 2020 Jul 1:ji1901512. doi: 10.4049/jimmunol.1901512.
PMID: 32611727
New Insights into the Immune System Using Dirty Mice.
J Immunol. 2020 Jul 1;205(1):3-11. doi: 10.4049/jimmunol.2000171.
PMID: 32571979
Frequency of MicroRNA Response Elements Identifies Pathologically Relevant Signaling Pathways in Triple-Negative Breast Cancer.
iScience. 2020 Jun 26;23(6):101249. doi: 10.1016/j.isci.2020.101249. Epub 2020 Jun 6.
PMID: 32629614
Polymer-mediated delivery of vaccines to treat opioid use disorders and to reduce opioid-induced toxicity.
Vaccine. 2020 Jun 19;38(30):4704-4712. doi: 10.1016/j.vaccine.2020.05.027. Epub 2020 May 19.
PMID: 32439214
Probiotics: Promise, Evidence, and Hope.
Gastroenterology. 2020 Jun 9:S0016-5085(20)34728-4. doi: 10.1053/j.gastro.2020.05.058.
PMID: 32531290
Comparative phenotypes of peripheral blood and spleen cells from cancer patients.
Cole KE, Ly QP, Hollingsworth MA, Cox JL, Stromnes IM, Padussis JC, Foster JM, Vargas LM, Talmadge JE.
Int Immunopharmacol. 2020 Jun 7;85:106655. doi: 10.1016/j.intimp.2020.106655. [Epub ahead of print]
PMID: 32521493
Instructing Memory in CD8+ Thymocytes.
Ashby KM, Hogquist KA.
Trends Immunol. 2020 Jun 6. pii: S1471-4906(20)30121-6. doi: 10.1016/j.it.2020.05.006. [Epub ahead of print]
PMID: 32518054
Different hierarchies of anti-modified protein autoantibody reactivities in rheumatoid arthritis.
Arthritis Rheumatol. 2020 Jun 5. doi: 10.1002/art.41385.
PMID: 32501655
TLR7/8 Agonist-Loaded Nanoparticles Augment NK Cell-Mediated Antibody-Based Cancer Immunotherapy.
Mol Pharm. 2020 Jun 1;17(6):2109-2124. doi: 10.1021/acs.molpharmaceut.0c00271. Epub 2020 May 21.
PMID: 32383885
Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice.
Elife. 2020 Jun 1;9:e57438. doi: 10.7554/eLife.57438.
PMID: 32479261
T Cell Receptor Engineered Lymphocytes for Cancer Therapy.
Curr Protoc Immunol. 2020 Jun;129(1):e97. doi: 10.1002/cpim.97.
PMID: 32432843
Probiotics: promise, evidence, and hope.
Khoruts A, Hoffmann DE, Britton RA.
Gastroenterology. 2020 May 25. pii: S0016-5085(20)34728-4. doi: 10.1053/j.gastro.2020.05.058. [Epub ahead of print] No abstract available.
PMID: 32531290
Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer.
Cancers (Basel). 2020 May 22;12(5):E1325. doi: 10.3390/cancers12051325.
PMID: 32455980
The Immune Landscape of Visceral Adipose Tissue During Obesity and Aging.
Front Endocrinol (Lausanne). 2020 May 15;11:267. doi: 10.3389/fendo.2020.00267. eCollection 2020.
PMID: 32499756
Polymer-mediated delivery of vaccines to treat opioid use disorders and to reduce opioid-induced toxicity.
Gradinati V, Baruffaldi F, Abbaraju S, Laudenbach M, Amin R, Gilger B, Velagaleti P, Pravetoni M.
Vaccine. 2020 May 19:S0264-410X(20)30646-0. doi: 10.1016/j.vaccine.2020.05.027.
PMID: 32439214
T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers.
Nat Med. 2020 May 11. doi: 10.1038/s41591-020-0858-8.
PMID: 32393800
Acquired Resistance to Immune Checkpoint Blockade Therapies.
Cancers (Basel). 2020 May 5;12(5):E1161. doi: 10.3390/cancers12051161.
PMID: 32380703
CD8+ T cells mediate ultraviolet A-induced immunomodulation in a model of extracorporeal photochemotherapy.
Hequet O, Nosbaum A, Guironnet-Paquet A, Blasco E, Nicolas-Virelizier E, Griffith TS, Rigal D, Cognasse F, Nicolas JF, Vocanson M.
Eur J Immunol. 2020 May;50(5):725-735. doi: 10.1002/eji.201948318. Epub 2020 Feb 10.
PMID: 32012249
Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance.
Dobson HE, Dias LDS, Kohn EM, Fites S, Wiesner DL, Dileepan T, Kujoth GC, Abraham A, Ostroff GR, Klein BS, Wüthrich M.
Mucosal Immunol. 2020 May;13(3):518-529. doi: 10.1038/s41385-019-0244-3. Epub 2020 Jan 3.
PMID: 31900406
Single Cell RNA Sequencing in Atherosclerosis Research.
Williams JW, Winkels H, Durant CP, Zaitsev K, Ghosheh Y, Ley K.
Circ Res. 2020 Apr 24;126(9):1112-1126. doi: 10.1161/CIRCRESAHA.119.315940. Epub 2020 Apr 23.
PMID: 32324494
NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4+ T Cells.
Hainberger D, Stolz V, Zhu C, Schuster M, Müller L, Hamminger P, Rica R, Waltenberger D, Alteneder M, Krausgruber T, Hladik A, Knapp S, Bock C, Trauner M, Farrar MA, Ellmeier W.
Front Immunol. 2020 Apr 3;11:579. doi: 10.3389/fimmu.2020.00579. eCollection 2020.
PMID: 32318068
Is the opioid use disorder epidemic impacting our immunological health?
Pravetoni M.
Brain Behav Immun. 2020 Apr 10. pii: S0889-1591(20)30487-6. doi: 10.1016/j.bbi.2020.04.022. [Epub ahead of print] No abstract available.
PMID: 32283290
Exploiting antibody biology for the treatment of cancer.
Khanna V, Panyam J, Griffith TS.
Immunotherapy. 2020 Mar 24. doi: 10.2217/imt-2019-0118. [Epub ahead of print]
PMID: 32208784
Evolutionarily conserved resistance to phagocytosis observed in melanoma cells is insensitive to upregulation of pro-phagocytic signals and to CD47 blockade.
Anderson KL, Snyder KM, Ito D, Lins DC, Mills LJ, Weiskopf K, Ring NG, Ring AM, Shimizu Y, Mescher MF, Weissman IL, Modiano JF.
Melanoma Res. 2020 Apr;30(2):147-158. doi: 10.1097/CMR.0000000000000629.
PMID: 31205227
Gut dysbiosis during antileukemia chemotherapy versus allogeneic hematopoietic cell transplantation.
Rashidi A, Kaiser T, Graiziger C, Holtan SG, Rehman TU, Weisdorf DJ, Dunny GM, Khoruts A, Staley C.
Cancer. 2020 Apr 1;126(7):1434-1447. doi: 10.1002/cncr.32641. Epub 2019 Dec 24.
PMID: 31873965
Developmental plasticity allows outside-in immune responses by resident memory T cells.
Fonseca R, Beura LK, Quarnstrom CF, Ghoneim HE, Fan Y, Zebley CC, Scott MC, Fares-Frederickson NJ, Wijeyesinghe S, Thompson EA, Borges da Silva H, Vezys V, Youngblood B, Masopust D,
Nat Immunol. 2020 Apr;21(4):412-421. doi: 10.1038/s41590-020-0607-7. Epub 2020 Feb 17.
PMID:32066954
Neutrophils Recirculate through Lymph Nodes to Survey Tissues for Pathogens.
Bogoslowski A, Wijeyesinghe S, Lee WY, Chen CS, Alanani S, Jenne C, Steeber DA, Scheiermann C, Butcher EC, Masopust D, Kubes P.
J Immunol. 2020 Mar 23. pii: ji2000022. doi: 10.4049/jimmunol.2000022. [Epub ahead of print]
PMID: 32205425
Impact of Repeated Cycles of EGF Bispecific Angiotoxin (eBAT) Administered at a Reduced Interval from Doxorubicin Chemotherapy in Dogs with Splenic Hemangiosarcoma.
Borgatti A, Fieberg A, Winter AL, Stuebner K, Taras E, Todhunter D, Masyr A, Rendhal A, Vallera DA, Koopmeiners JS, Modiano JF.
Vet Comp Oncol. 2020 Mar 18. doi: 10.1111/vco.12590. [Epub ahead of print]
PMID: 32187827
Recent advances in iNKT cell development.
Hogquist K, Georgiev H.
F1000Res. 2020 Feb 20;9. pii: F1000 Faculty Rev-127. doi: 10.12688/f1000research.21378.1. eCollection 2020. Review.
PMID: 32148771
Blood and tissue biomarker analysis in dogs with osteosarcoma treated with palliative radiation and intra-tumoral autologous natural killer cell transfer.
Judge SJ, Yanagisawa M, Sturgill IR, Bateni SB, Gingrich AA, Foltz JA, Lee DA, Modiano JF, Monjazeb AM, Culp WTN, Rebhun RB, Murphy WJ, Kent MS, Canter RJ.
PLoS One. 2020 Feb 21;15(2):e0224775. doi: 10.1371/journal.pone.0224775. eCollection 2020
PMID:32084139
Interruption of continuous opioid exposure exacerbates drug-evoked adaptations in the mesolimbic dopamine system.
Lefevre EM, Pisansky MT, Toddes C, Baruffaldi F, Pravetoni M, Tian L, Kono TJY, Rothwell PE.
Neuropsychopharmacology. 2020 Feb 20. doi: 10.1038/s41386-020-0643-x. [Epub ahead of print]
PMID:32079024
Myocardial B cells are a subset of circulating lymphocytes with delayed transit through the heart.
Adamo L, Rocha-Resende C, Lin CY, Evans S, Williams J, Dun H, Li W, Mpoy C, Andhey PS, Rogers BE, Lavine K, Kreisel D, Artyomov M, Randolph GJ, Mann DL.
JCI Insight. 2020 Feb 13;5(3). pii: 134700. doi: 10.1172/jci.insight.134700.
PMID: 31945014
PD-1+ stemlike CD8 T cells are resident in lymphoid tissues during persistent LCMV infection.
Im SJ, Konieczny BT, Hudson WH, Masopust D, Ahmed R.
Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4292-4299. doi: 10.1073/pnas.1917298117.
PMID: 32034098
Integrating resident memory into T cell differentiation models.
Rosato PC, Wijeyesinghe S, Stolley JM, Masopust D.
Curr Opin Immunol. 2020 Feb 1;63:35-42. doi: 10.1016/j.coi.2020.01.001. [Epub ahead of print] Review.
PMID: 32018169
Interactions between the gut microbiome and host gene regulation in cystic fibrosis.
Dayama G, Priya S, Niccum DE, Khoruts A, Blekhman R.
Genome Med. 2020 Jan 28;12(1):12. doi: 10.1186/s13073-020-0710-2.
PMID: 31992345
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance.
ElTanbouly MA, Zhao Y, Nowak E, Li J, Schaafsma E, Le Mercier I, Ceeraz S, Lines JL, Peng C, Carriere C, Huang X, Day M, Koehn B, Lee SW, Silva Morales M, Hogquist KA, Jameson SC, Mueller D, Rothstein J, Blazar BR, Cheng C, Noelle RJ.
Science. 2020 Jan 17;367(6475). pii: eaay0524. doi: 10.1126/science.aay0524.
PMID: 31949051
Vitamin D3-mediated resistance to a multiple sclerosis model disease depends on myeloid cell 1,25-dihydroxyvitamin D3 synthesis and correlates with increased CD4+ T cell CTLA-4 expression.
Spanier JA, Nashold FE, Nelson CD, Praska CE, Hayes CE.
J Neuroimmunol. 2020 Jan 15;338:577105. doi: 10.1016/j.jneuroim.2019.577105. Epub 2019 Nov 7.
PMID: 31731231