Fellowship dates: 2011-14
Research Emphasis: Developed a novel, highly-sensitive approach that allowed me to investigate the differentiation of single naive CD4+ T cells into different types of effector and memory cells. Showed that the strength of signal that a given CD4+ T cell receives through its unique T cell receptor plays a previously unappreciated role in the commitment of cells to the Th1 and Tfh lineages. Further demonstrated that essentially all naive CD4+ T cells produce memory cells after infection. Collectively, these findings provided a framework for understanding the variability of immune responses between different individuals.
Current Position: Institute Group Leader - ECLIPSE at MD Anderson Cancer Center, Houston, TX
Contac [email protected]