Siddheshvar Bhela, Ph.D.

Biography

Fellowship dates: 2017-2021
Research Emphasis: Investigating mechanisms controlling generation and maintenance of peripheral T cell tolerance. Researching role of tolerant CD8 T cells in regulating autoimmunity and cancer. Understanding autoimmunity in the context of hygiene hypothesis.

Siddheshvar Bhela

Emily Thompson, Ph.D

Biography

Program: MICaB
Defense Year: 2017
Advisor: Vaiva Vezys
Dissertation Title: "Visualizing CD8+ T cell responses to foreign and self-antigen"

Current Position: Associate Director, T Cell Biology, Kelonia Therapeutics, Cambridge, MA
Contact Info: [email protected]

Emily Thompson, Ph.D

Christine Nelson, Ph.D.

Biography

Program: MICaB
Defense Year: 2018
Advisor: Vaiva Vezys
Dissertation Title: "Function and utility of self-specific CD8 T cells."

Current Position: Postdoctoral Fellow, National Institute of Allergy and Infectious Diseases
Contact Info:[email protected]

Christine Nelson, Ph.D.

Vezys Lab

Graduate Students and Post Doctoral Fellows in the the Vezys lab study CD8 and CD4 T cell responses in autoimmunity and chronic infections. Specifically, the laboratory is examining how persistent interaction with cognate antigen impacts T cell selection, differentiation and survival. They observe and manipulate the dynamics of T cell responses specific for chronic viral infections or host derived self-proteins using MHC tetramers, adoptive transfer of transgenic T cells and fluorescence flow cytometry.