Sophie Hapak, M.D.

Biography

Fellowship dates: 2020-2024
Mentor: Vaiva Vezys (Lab website)
Research Emphasis: Immunological mechanisms of immune mediated adverse events (irAE's) in checkpoint inhibitor therapy. List of Publications

Sophie Hapak, MD

Siddheshvar Bhela, Ph.D.

Biography

Fellowship dates: 2017-2021
Research Emphasis: Investigating mechanisms controlling generation and maintenance of peripheral T cell tolerance. Researching role of tolerant CD8 T cells in regulating autoimmunity and cancer. Understanding autoimmunity in the context of hygiene hypothesis.

Siddheshvar Bhela

Emily Thompson, Ph.D

Biography


Program: MICaB
Year Entered: 2011
Defense Year: 2017
Advisor: Vaiva Vezys
Dissertation Title: "Visualizing CD8+ T cell responses to foreign and self-antigen"

Degrees received: 
B.S., University of Wisconsin-Madison, 2009
Ph.D., University of Minnesota-Twin Cities, 2017

Emily Thompson, Ph.D

Christine Nelson, Ph.D.

Biography


Program: MICaB
Year Entered: 2012
Defense Year: 2018
Advisor: Vaiva Vezys
Dissertation Title: "Function and utility of self-specific CD8 T cells."

Degrees received: 
B.S., University of Minnesota, TC, 2007
Ph.D., University of Minnesota, TC, 2018

Christine Nelson, Ph.D.

Vezys Lab

Graduate Students and Post-Doctoral Fellows in the Vezys lab study CD8 and CD4 T cell responses in autoimmunity and chronic infections. Specifically, the laboratory is examining how persistent interaction with cognate antigen impacts T cell selection, differentiation and survival. They observe and manipulate the dynamics of T cell responses specific for chronic viral infections or host-derived self-proteins using MHC tetramers, adoptive transfer of transgenic T cells and fluorescence flow cytometry.